Analysis of the news of July 20, 2022

Study highlights overuse of broad-spectrum antibiotics in Saudi Arabia

An analysis of dental and pediatric primary care practices in Saudi Arabia found higher prescribing of broad-spectrum antibiotics and poor adherence to antibiotic prescribing guidelines, researchers reported yesterday in the American Journal of Infection Control.

The retrospective cross-sectional study, conducted from May to November 2020 in 24 primary healthcare centers in Saudi Arabia, assessed antibiotic prescribing patterns in family medicine and dental practices using the AWARe classification system (Access, Surveillance and Reserve) from the World Health Organization and relevant clinics. guidelines. The researchers also identified factors associated with the choice of Watch-group antibiotics, which are broader-spectrum agents with higher resistance potential.

Of the 752 antibiotic prescriptions evaluated, 84% were prescribed by general practitioners and 16% by dentists, most often for urinary (12.8%) and acute respiratory (12.2%) infections. Compared to Access group antibiotics, Watch group antibiotics such as second-generation cephalosporins and macrolides were more likely to be prescribed based on number of prescriptions (51.1% vs. 48.9%) and doses Defined Daily Benefits (DDD) (52.2% versus 47.8%).

The Watch-group antibiotic percentages for children and adults were 66.7% and 42.9%, respectively. Overall adherence to clinical prescribing guidelines for children, adults, and total number of antibiotics prescribed was 27.2%, 64%, and 49.5%, respectively, with dental clinics showing better adherence than dental practices. general.

A multivariate logistic regression analysis revealed that being a child (adjusted odds ratio, [aOR], 2.89; 95% confidence interval [CI]1.46 to 5.78), the diagnosis of acute respiratory tract infection (ORa, 2.62; 95% CI, 1.03 to 6.69) and urinary tract infection (ORa, 4, 69; 95% CI, 2.09 to 10.56) were associated with higher prescription of Watch-group antibiotics.

The study authors say the findings indicate that national guidelines on antibiotic use are needed in Saudi Arabia, as well as a surveillance system to track antibiotic use nationally.

“The Watch Group’s higher proportion of antibiotic prescriptions in this study for children and adults is a warning sign that may reflect inappropriate awareness of optimal antibiotic selection as well as poor compliance with guidelines,” they wrote. “This finding may lead to a potential increase in bacterial resistance and overuse of broad-spectrum antibiotics, which consequently increases costs and the likelihood of adverse drug reactions or reduced treatment outcomes.”
Jul 19 Infection control Am J abstract

Florida’s first local dengue fever case triggers health alert

The Florida Department of Health announced a mosquito-borne illness advisory this week after the first local dengue illness of 2022 was identified in a Miami-Dade County resident.

Officials urged people to take preventative measures, such as draining standing water from items such as buckets and flowerpots and wearing protective clothing and mosquito repellent. They also issued a reminder about symptoms, which can be asymptomatic or mild, but can also include fever, headache, eye pain and musculoskeletal pain.

Dengue fever is transmitted by Aedes mosquitoes. Local cases of dengue are not uncommon in South Florida. Last year, no cases were reported in Florida, but in 2020 authorities recorded 71 locally acquired cases, according to the Centers for Disease Control and Prevention (CDC).
July 18 Florida Department of Health Statement
General Dengue Information from the CDC

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